CRPS-RISE Study

CRPS Research for Brighter Moments.

CRPS‑RISE is a clinical research trial that is studying an investigational medicine for adults living with Complex Regional Pain Syndrome Type 1 (CRPS‑1).

This is a pivotal Phase 3, triple-blind, placebo-controlled clinical research trial evaluating an investigational medicine called neridronate.

Participants are randomly assigned (by chance) to receive either:

  • The investigational medicine (neridronate), or
  • A placebo (looks like neridronate but does not contain any active ingredients or drug in it)

Why Consider Participating in a Clinical Research Trial?

By taking part in this trial, you may:

  • Help advance research for people living with CRPS
  • Contribute to the development of potential future treatments
  • Receive trial-related care at no cost

Participation is voluntary, and you may withdraw from the trial at any time.

CRPSStudy

CRPS-RISE will include about 270 adults who have CRPS-1. To participate this clinical trial, you must:

  • Be 18 years or older
  • Have the “warm subtype” of CRPS-1, meaning the affected limb is red, warm, or/and swollen
  • Have developed CRPS symptoms within the last 6 months
  • There are other considerations a trial doctor can discuss with you.

If you qualify and are interested in partaking in this study, please fill out the following:

Which of the following symptoms are you currently experiencing in the affected arm or leg? (Select all that apply)(Required)